A Legacy to Remember
 
This general brochure reviews thirty years of progress of the Retina Research Foundation in the drive to cure retinal disease.  It is an exciting presentation of the Pioneers in Retina and their efforts to provide the understanding, technology and skills required in this important and intricate field and to ensure their understanding and use worldwide.

RRF Newsletter

Published quarterly, this Newsletter includes information on the latest developments in  retinal technology, drugs, and surgical techniques in treating retinal disease. It also highlights those scientists who are making history in this field and recognizes those who have made significant financial contributions to retina research.

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2007 Bibliographies
 

Suping Cai and Curtis Brandt: “Induction of interleukin-6 in human retinal epithelial cells by an attenuated Herpes simplex virus vector requires viral replication and NFkB activation” Experimental Eye Research, 2007.

Sang-Chui Nam, Bibhash Mukhopadhyay, Kwang-Wook Choi: “Antagonistic functions of Par-1 kinase and protein phosphatase 2A are required for localization of Bazooka and photoreceptor morphogenesis in Drosophila”, Science Direct, Developmental Biology 306 (2007) 624-635.

Kwang-Wook Choi, Sang-Chui Nam, Bibhash Mukhopadhyay: “Par-1 and PP2A: Yin-Yang of Bazooka Localization”, 235-237 July/August 2007 Landes Bioscience.

Ya-Chieh Hsu, Joshua J.C. Chern, Yi Cai, Mingyao Liu & Kwang-Wook Choi : “Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase” Nature, Volume 445, February 15, 2007.

Ramon L. Font, Maria Del Valle, Jose Avedano, Marc Longo, Milton Boniuk: “Primary adenoid cystic carcinoma of the conjunctive arising from the accessory lacrimal glands” Cornea, 2007.

Lalita Wadhwa, Mary Y. Hurwitz, Patricia Chévez-Barrios, and Richard L. Hurwitz: “Treatment of Invasive Retinoblastoma in a Murine Model Using an Oncolytic Picornavirus” Cancer Res 2007: 67(22) November 15, 2007.

Saumya R. Chaudhuri, Joshua N. Mallam, Patricia Chévez-Barrios, Lalita Wadhwa, Philip Ng, Mary Y. Hurwitz and Richard L. Hurwitz: “Modulation of Adenoviral Transduction In Vitro and In Vivo by Hyaluronan and its Receptor CD44” Molecular Therapy, Vol. 15 No. 3, 566-570, March 2007.

Kathryn L. Pepple, Aimee E. Anderson, Benjamin J. Frankfort and Graeme Mardon: “A Genetic Screen in Drosophila for Genes Interacting With senseless During Neuronal Development Identifies the Importin moleskin” Genetics 175: 125-141.

Taiji Nagaoka, Travis W. Hein, Akitoshi Yoshida, and Lih Kuo:  “Resveratrol, A component of Red Wine, Elicits Dilation of Isolated Porcine Retinal Arterioles: Role of Nitric Oxide and Potassium Channels” Investigative Ophthalmology & Visual Science, September, 2007, Vol 48, No. 9

Taiji Nagaoka, Travis W. Hein, Akitoshi Yoshida, and Lih Kuo:  “Simvastin Elicits Dilation of Isolated Porcine Retinal Arterioles: Role of Nitric Oxide and Mevalonate-Rho Kinase Pathways” Investigative Ophthalmology & Visual Sciences, February 2007, Vol, 48. No.2.

Paul R. van Ginkel, Dhruv Sareen, Lalita Subramanian, Quintisha Walker, Soesiawati R. Darjatmoko, Mary J. Lindstrom, Amol Kulkarni, Daniel M. Albert, and Arthur S. Polans: “Reveratrol Inhibits Tumor Growth of Human Neuroblastoma and Mediates Apoptosis by Directly Targeting Mitochondria” Clin Cancer Res 2007:12(17) September 1, 2007.

Dhruv Sareen, Soesiawati R. Darjatmoko, Daniel M. Albert and Arthur S. Polans: “Mitochondria, Calcium and Calpain are Key Mediators of Resveratrol-induced Apoptosis in Breast Cancer” Molecular Pharmacology Fast Forward, September 11, 2007.

Shuji Kondo. Elizabeth A. Scheef, Nader Sheibani, and Christine M. Sorenson: “PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis: Am J Physical Cell Physiol 292:C2070-C2082, 2007.

Janee Gelineau-van-Waes, Lynette Smith, Michael van Waes, Justin Wilberding, James D. Eudy, Linda K. Bauer and Joyce Maddox: “Altered Expression of the Iron Transporter Nramp1 (Sic11a1) during Fetal Development of the retinal pigment epithelium in microphthalmia-Associated Transcription Factor Mift-mi and Mitf-vitiligo Mouse Mutants” Experimental Eye Research, 2007.

Mark E. Pennesi, Debra E. Bramblett, Jang-Hyeon Cho, Ming-Jer Tsai, Samuel M. Wu: “A Role for BHLH Transcription Factors in Retinal Degeneration and dysfunction” Experimental Medicine and Biology, Vol. 572, 155-161.

Muhammad M. Abd-El Barr, Kristen Sykoudis, Sara Andrabi, Erica R. Eichers, Mark E. Pennesi, Perciliz L. Tan, John H. Wilson, Nicholas Katsanis, James R. Lupski, Samuel M. Wu: “Impaired photoreceptor protein transport and synaptic transmission in a mouse model of Bardet-Biedl syndrome” Vision Research (2007) doi:10:1016; 2007.

Samuel Wu: “Retinal Bipolar Cells” New Encyclopedia of Neuroscience, in press.