RRF Chair at University of Wisconsin

Examining mouse retinal wholemount for neovascularization after oxygen-induced ischemic retinopathy

Nader Sheibani, PhD

Ophthalmology and Visual Sciences

University of Wisconsin

Madison, WI

Dr. Sheibani’s Research Project

Regulation of Ocular Vascular Development and Neovascularization

Current Research Interests

Dr. Sheibani’s work focus on the mechanisms that regulate ocular vascular function. Using this knowledge, he is developing novel treatments. He recently showed intravitreal ocular safety of propranolol and its efficacy in attenuation of CNV. In collaboration with Dr. Zhang at Northwestern he demonstrated the utility of visible light OCT for measuring retinal oxygen metabolic response. In collaboration with Dr. Shah he showed the important role of mitochondrial carbonic anhydrases in high glucose-mediated toxicity of pericytes. He also published two review on functional role of inorganic trace elements in angiogenesis and one the importance of PECAM-1, eNOS, and endoglin axis in angiogenesis (reported in: IOVS (Dec 2015), LSA (Sept 2015), CROH (May 2015), JOVR (March 2015), Clin Sci (Aug 2015), and Physiol Rep (Jan 2015)).

Microglia in the mouse retina.

Analysis of DNA for screening transgenic mice

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Mission of RRF

The mission of the Retina Research Foundation is to reduce retinal blindness worldwide by funding programs in research and education. As a public charity, RRF raises funds from the private sector and the investment of its endowment funds.

Reducing Retinal Blindness Worldwide